Succinate Dehydrogenase

A flavoprotein containing oxidoreductase that catalyzes the dehydrogenation of SUCCINATE to fumarate. In most eukaryotic organisms this enzyme is a component of mitochondrial electron transport complex II.

Also Known As:

Fumarate Reductase; Succinic Dehydrogenase; Dehydrogenase, Succinate; Dehydrogenase, Succinic; Oxidase, Succinic; Reductase, Fumarate; Succinic Oxidase

Macromolecular Substances: 97
- Multiprotein Complexes: 128
  - Multienzyme Complexes: 8
    - Succinate Cytochrome c Oxidoreductase: 31
      - Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1968
Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Oxidoreductases: 13899
    - Succinate Cytochrome c Oxidoreductase: 31
      - Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1968
    - Oxidoreductases Acting on CH-CH Group Donors
      - Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1968
  - Multienzyme Complexes: 8
    - Electron Transport Chain Complex Proteins
      - Electron-Transferring Flavoproteins: 83
        Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1968
      - Succinate Cytochrome c Oxidoreductase: 31
        Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1968
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Carrier Proteins: 13306
    - Iron-Binding Proteins: 176
      - Nonheme Iron Proteins
        Iron-Sulfur Proteins: 44
        Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1968
  - Membrane Proteins: 10262
    - Electron Transport Chain Complex Proteins
      - Electron-Transferring Flavoproteins: 83
        Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1968
      - Succinate Cytochrome c Oxidoreductase: 31
        Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1968
  - Flavoproteins: 240
    - Electron-Transferring Flavoproteins: 83
      - Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1968
  - Metalloproteins: 169
    - Iron-Binding Proteins: 176
      - Nonheme Iron Proteins
        Iron-Sulfur Proteins: 44
        Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1968

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Disease

Drug/Important Bio-Agent (IBA)